Table 6.

Estimated p Values and Effect Sizes for Comparisons of Microglia Morphological Outcomes in the Hypothalamus Among Injury × Time Post-Injury Group Combinations from Generalized Linear Mixed Models With Negative-Binomial or Poisson Error Distributions

Comparison	No. microglia		No. branches		Branch length		No. end-points
	p value	Effect size	p value	Effect size	p value	Effect size	p value	Effect size
Sham 1 DPI vs. TBI 1 DPI	0.99	0.02	0.82	0.01	0.86	<0.001	0.81	0.01
Sham 1 DPI vs. sham 7 DPI	0.97	0.10	0.99	0.001	0.99	<0.001	0.99	0.002
Sham 1 DPI vs. sham 25 DPI	0.21	0.36	0.83	0.01	0.99	<0.001	0.25	0.1
TBI 1 DPI vs. TBI 7 DPI	0.99	0.02	0.99	<0.001	0.99	<0.001	0.93	0.01
TBI 1 DPI vs. TBI 25 DPI	0.12	0.40	0.12	0.01	0.46	<0.001	0.002	0.02
Sham 7 DPI vs. TBI 7 DPI	0.99	0.06	0.97	0.003	0.95	<0.001	0.98	0.004
Sham 7 DPI vs. sham 25 DPI	0.62	0.27	0.76	0.01	0.92	<0.001	0.56	0.01
TBI 7 DPI vs. TBI 25 DPI	0.14	0.38	0.16	0.01	0.33	<0.001	0.03	0.02
Sham 25 TBI vs. TBI 25 DPI	0.99	0.05	0.99	<0.001	0.99	<0.001	0.99	0.002

Statistical significance was achieved if p < 0.05, whereas biological significance was achieved if effect size >0.20. Bold values denote biologically important effects.

DPI, days post-injury; TBI, traumatic brain injury.