Table 1.
Multivariate Cox regression of GC patients’ prognosis in Cohort 3
| Characteristics | Classification | P-value | Hazard ratio | 95% Cl |
|---|---|---|---|---|
| TNM staging | I | 0.010 | Reference | |
| II | 1.19 | 0.07–20.88 | ||
| III | 4.02 | 0.24–66.59 | ||
| IV | 12.86 | 0.70–237.08 | ||
| Macroscopic appearance | Borrmann I | 0.789 | Reference | |
| Borrmann II | 3.69 | 0.47–28.78 | ||
| Borrmann III | 3.35 | 0.43–25.97 | ||
| Borrmann IV | 3.45 | 0.41–29.25 | ||
| EGC | 1.96 | 0.06–60.26 | ||
| Vascular tumor embolus | No | 0.463 | Reference | |
| Yes | 1.38 | 0.59–3.24 | ||
| Metabolic risk factor* | Low | 5.276 × 10−5 | Reference | |
| High | 7.53 | 2.83–20.04 |
Multivariate Cox regression was applied to the 28-PM model and clinical parameters to identify independent prognostic factors. Parameters with P < 0.05 are recognized as statistically significant, signifying their role as independent prognostic factors for GC. P-values were calculated based on data from n = 179 independent patient samples and Wald test.
CI confidence interval, EGC early gastric cancer.
*The classifier was derived from the 28-PM model cutoff value, represents as a high-risk group and a low-risk group for the GC patients.