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. 2024 Feb 23;8:47. doi: 10.1038/s41698-024-00531-y

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — (Left) Data used to define PRACME signature include The Cancer Genome Atlas mesothelioma (TCGA-MESO) and private multi-regional MPM patients data. (Right) Detailed steps of selecting final signature with color green to indicate prognostic gene selection and color pink to indicate clonal gene selection.