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. 2024 Feb 23;8:47. doi: 10.1038/s41698-024-00531-y

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 5 — a Univariable and Multivariable Cox regression models on Bueno, Bott and TCGA MPM datasets. b Univariable and Multivariable Cox regression models on Lee, Okayama and Shedden datasets; Each segment represents hazard ratio and 95-percent confidence interval. Red indicates PRACME, black indicates ORACLE. Vertical dash-line represents hazard ratio of 1.0. c Gene-level copy number variation correlation with amplification frequency on the left and deletion frequency on the right. X-axis represents LUAD gene-level CNV and y-axis represents MESO gene-level CNV. d Chromosome-band level CNV correlation with amplification frequency on the left panel and deletion frequency on the right panel. e Correlation of PRACME and ORACLE in Bueno MPM patients (top) and Okayama LUAD patients (bottom). f Overlapping Q4 genes in MESO (yellow) and in LUAD (red). g Overlapping prognostic genes in TCGA-MESO (yellow) and TCGA-LUAD (red).