Table 2.
Cox regression of all-cause death in the overall MAFLD patients.
| Variables | Univariate | Multivariate | ||
|---|---|---|---|---|
| HR (95% CI) | P value | HR (95% CI) | P value | |
| HEI score | 1.002 (0.999–1.006) | 0.219 | 0.995 (0.992–0.999) | 0.017 |
| PA level | 0.999 (0.999–1.000) | 0.018 | 0.999 (0.999–1.000) | 0.029 |
| Male, n (%) | 1.305 (1.181–1.442) | <0.001 | 1.156 (1.020–1.310) | 0.024 |
| Age (years) | 1.081 (1.076–1.085) | <0.001 | 1.067 (1.06–1.074) | <0.001 |
| Race, n (%) | 1.042 (0.928–1.171) | 0.485 | 1.228 (1.081–1.396) | 0.002 |
| Low educational level | 1.662 (1.503–1.837) | <0.001 | 1.098 (0.983–1.226) | 0.099 |
| Low family income | 0.916 (0.812–1.033) | 0.153 | 1.128 (0.992–1.284) | 0.066 |
| Overdrink, n (%) | 1.171 (0.956–1.434) | 0.126 | 1.323 (1.072–1.633) | 0.009 |
| Type 2 diabetes, n (%) | 2.691 (2.427–2.984) | <0.001 | 1.150 (1.005–1.315) | 0.042 |
| Hypertension, n (%) | 2.405 (2.145–2.697) | <0.001 | 1.207 (1.070–1.361) | 0.002 |
| BMI (kg/m2) | 1.009 (1.001–1.016) | 0.027 | 0.996 (0.985–1.008) | 0.509 |
| WHR | 46.218 (32.819–65.087) | <0.001 | 4.790 (2.303–9.963) | <0.001 |
| HbA1c (%) | 1.230 (1.200–1.260) | <0.001 | 1.103 (1.064–1.143) | <0.001 |
| Cholesterol (mmol/L) | 1.223 (1.182–1.266) | <0.001 | 0.997 (0.951–1.045) | 0.892 |
| Triglyceride (mmol/L) | 1.075 (1.054–1.097) | <0.001 | 1.038 (1.006–1.071) | 0.021 |
| AST (U/L) | 1.003 (1.001–1.006) | 0.014 | 1.010 (1.005–1.015) | <0.001 |
| ALT (U/L) | 0.992 (0.989–0.995) | <0.001 | 0.991 (0.987–0.996) | <0.001 |
| eGFR (ml/min/1.73m2) | 0.960 (0.957–0.963) | <0.001 | 0.994 (0.990–0.998) | 0.003 |
| FIB-4 scores | 1.443 (1.407–1.481) | <0.001 | 1.069 (0.961–1.189) | 0.217 |
| NFS scores | 1.541 (1.497–1.587) | <0.001 | 1.021 (0.961–1.086) | 0.500 |
MAFLD Metabolic (dysfunction-) associated fatty liver disease, HEI healthy Eating Index, BMI, body mass index, WHR Waist hip ratio, HbA1c glycosylated hemoglobin, ALT alanine aminotransferase, AST aspartate aminotransferase, eGFR estimated glomerular filtration rate, FIB-4 fibrosis 4 index; NFS NAFLD fibrosis score.