FIG. 6.

Transactivation abilities of RET mutants. Cos cells were transfected with a constant amount (5 μg) of the TRE-TK-CAT reporter gene and three different molar ratios (from left to right, for each expression vector, 1:1, 1:2, and 1:3) of each of the expression vectors for protoRET, RET2A, HSCR32, protoRET-Flag, and RET2A-Flag. Each CAT activity is reported as relative induction and represents the mean of at least three independent experiments performed with different DNA preparations. Standard deviations are indicated by error bars.