Fig. 4.

PPC demonstrates competitive binding to the peptide domains of both KEAP1 and Nrf2. A Molecular docking analysis highlighting the interaction between PPC (orange) and KEAP1 (blue). B Docking analysis showcasing the interaction between Nrf2 (orange) and KEAP1 (blue). Grey dotted lines denote hydrophobic interactions, blue solid lines signify hydrogen bonds, and yellow dotted lines represent salt bridges. Amino acids within red boxes mark the consistent binding regions of both PPC and Nrf2 to the KEAP1 peptide.