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. 2024 Jan 12;13(1):139–151. doi: 10.21037/tlcr-23-756

Table 6. Multiple analysis of pneumonitis in chemoradiation combined with ICI.

Characteristics Pneumonitis grade ≥2 Pneumonitis grade ≥3
OR 95% CI P value OR 95% CI P value
Median age 1.062 0.985–1.145 0.118
Stage (III vs. IV) 2.082 0.625–6.934 0.232
ICI (PD-1 vs. PD-L1)
History of chronic lung disease (no vs. yes) 8.351 1.469–47.484 0.017
Median dose 0.318 0.094–1.081 0.318 0.293 0.61–1.414 0.126
V5 1.100 0.562–2.155 0.780
V20 1.382 0.708–2.698 0.343
V30
PTV 0.924 0.451–1.892 0.829

ICI, immune checkpoint inhibitor; OR, odds ratio; CI, confidence interval; PD-1, programmed cell death protein-1; PD-L1, programmed death ligand-1; PTV, planned target volume.