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Clonal evolution upon treatment. For the 54 patients who benefited from a karyotype at inclusion and after treatment, data comparison allowed to identify three patterns of respectively (i) acquisition of a new abnormality in a previously known clone (clonal evolution), (ii) appearance of new clones (different), or (iii) no change (identical). Of note, this led a few patients to change of cytogenetic risk, respectively from adverse (green) to intermediate and vice versa (Orange).
