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Proposed mechanisms of action of niosomes for dermal and transdermal applications: (A) drug molecules are released by niosomes; (B) niosome constituents act as penetration enhancers; (C) niosome adsorption and/or fusion with Stratum Corneum; (D) intact niosome penetration through the intact skin; (E) niosome penetration through hair follicles and/or pilosebaceous units. Reproduced from [9] with permission.
