Table 2.
Results of one-pot synthesis of esters 8–14.
| Product | R1 | R2 | Solvent | Reaction Time (h) |
Reaction Temperature |
Yield (%) a |
|---|---|---|---|---|---|---|
| 8 | CH3 |
|
DCM | 10 | r.t. | 97 |
| 9 |
|
|
DCM | 18 | r.t. | 50 |
| 10 |
|
|
DCM | 20 | r.t. | 40 |
| 11 |
|
|
Toluene | 4 | reflux | 84 |
| 12 |
|
|
Hexane | 10 | r.t. | 81 |
| 13 |
|
|
Hexane | 10 | r.t. | 67 |
| 14 |
|
(CH3)2CH | Hexane | 10 | r.t. | 70 |
a isolated yields.