Figure 6.
Lung compliance in antitoxin and antitoxin-ciprofloxacin treated mice 30 days following ricin intoxication. Mice were intranasally intoxicated with 2LD50 (7 µg/kg) ricin. Antitoxin was administered at 24 h PE. Ciprofloxacin (200 mg/kg) was administered daily to the relevant group intraperitoneally at 24, 48, 72, and 96 h PE. Sham group was administered PBS instead of either ricin or antitoxin. At 30 days PE, lung compliance was determined. n = 8, 11, and 12 per group. Data are expressed as means ± SEM. * p < 0.05, ** p < 0.01, n.s., not significant.