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. 2024 Feb 12;17(2):240. doi: 10.3390/ph17020240

Figure 5.

Figure 5

Anti-SARS-CoV-2 effect of Mpro inhibitors. Quantification of the cytopathic effect elicited by SARS-CoV-2 in Vero CCL81 after 72 h in the presence of (a) the positive control, GC376; (b) compound 13; or (ce) analogs 13ac. The maximal concentration tested for each compound was determined by evaluating its cytotoxicity in uninfected cells. Graphs show the mean percent reduction in the cytopathic effect from three technical replicates ± SEM. A representative curve is shown from two independent experiments performed.

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