Table 3.
Hazard ratios (95% CI) for the incidence of NAFLD according to 24-h urinary sodium excretion.
| Hazard Ratio (95% CI) | p-Value | |||
|---|---|---|---|---|
| T1 | T2 | T3 | ||
| All (n = 2582) | 861 | 861 | 860 | |
| Incident case, n (%) | 139 (16.14) | 182 (21.13) | 203 (23.60) | <0.001 |
| Crude analysis | Ref | 1.32 (1.06, 1.65) | 1.55 (1.25, 1.92) | <0.001 * |
| Multivariate analysis | Ref | 1.31 (1.05–1.64) | 1.54 (1.24–1.92) | <0.001 * |
| Men (n = 1011) | 337 | 337 | 337 | |
| Incident case, n (%) | 49 (14.54) | 58 (17.21) | 66 (19.58) | 0.174 |
| Crude analysis | Ref | 1.18 (0.80, 1.72) | 1.41 (0.98, 2.04) | 0.064 * |
| Multivariate analysis | Ref | 1.19 (0.81, 1.75) | 1.50 (1.02, 2.19) | <0.001 * |
| Females (n = 1571) | 524 | 524 | 523 | |
| Incident case, n (%) | 90 (17.17) | 124 (23.66) | 137 (26.19) | 0.001 |
| Crude analysis | Ref | 1.40 (1.07, 1.84) | 1.62 (1.24, 2.12) | <0.001 * |
| Multivariate analysis | Ref | 1.35 (1.03, 1.78) | 1.51 (1.15, 1.98) | 0.003 * |
Multivariate analysis in all subjects: age, smoking status, triglyceride, total cholesterol, estimated glomerular filtration rate (eGFR), homeostatic model assessment of insulin resistance (HOMA-IR), hypertension, postmenopausal status. Multivariate analysis in males: age, physical activity, triglyceride, albumin, eGFR, and hyperlipidemia. Multivariate analysis in females: triglyceride, total cholesterol, albumin, HOMA-IR, and hypertension. * p-values were analyzed using the trend of the odds test. NAFLD, nonalcoholic fatty liver disease; CI, confidence interval; T1, lowest tertile; T2, middle tertile; T3, highest tertile.