Table 4.
Hazard ratios (95% CI) for the incidence of hepatic fibrosis according to the 24-h urinary sodium excretion.
| Hazard Ratio (95% CI) | p-Value | |||
|---|---|---|---|---|
| T1 | T2 | T3 | ||
| All (n = 2582) | 861 | 861 | 860 | |
| Incident case, n (%) | 21 (2.43) | 48 (5.57) | 49 (5.69) | 0.001 |
| Crude analysis | Ref | 2.25 (1.35, 3.77) | 2.37 (1.42, 3.95) | 0.001 * |
| Multivariate analysis | Ref | 2.26 (1.35, 3.78) | 2.28 (1.36, 3.83) | 0.003 * |
| Men (n = 1011) | 337 | 337 | 337 | |
| Incident case, n (%) | 7 (2.07) | 17 (5.04) | 18 (5.34) | 0.178 |
| Crude analysis | Ref | 1.87 (0.83, 4.19) | 2.04 (0.91, 4.55) | 0.083 * |
| Multivariate analysis | Ref | 1.93 (0.85, 4.36) | 2.14 (0.95, 4.86) | 0.073 * |
| Females (n = 1571) | 524 | 524 | 523 | |
| Incident case, n (%) | 12 (1.90) | 31 (4.77) | 31 (5.73) | 0.007 |
| Crude analysis | Ref | 2.54 (1.30, 4.95) | 2.61 (1.34, 5.09) | 0.005 * |
| Multivariate analysis | Ref | 2.49 (1.27, 4.86) | 2.42 (1.23, 4.73) | 0.015 * |
Multivariate analysis in all subjects: triglyceride, estimated glomerular filtration rate (eGFR), hypertension, postmenopausal status. Multivariate analysis in males: triglyceride, homeostatic model assessment of insulin resistance (HOMA-IR), eGFR, and hypertension. Multivariate analysis in females: triglyceride, eGFR, hypertension, and postmenopausal status. * p-values were analyzed using the trend of odds test. CI, confidence interval; T1, lowest tertile; T2, middle tertile; T3, highest tertile.