Skip to main content
. 2024 Jan 30;12(2):144. doi: 10.3390/vaccines12020144

Figure 3.

Figure 3

Neutralization against Omicron sublineages BA.4/5, XBB.1.5, XBB.1.16, and EG.5.1 in individuals with or without a history of infection by SARS-CoV-2. (A) NT50 values of sera from older adults without (n = 22) and with (n = 37) infection history, against D614G, Omicron BA.4/5, XBB.1.5, XBB.1.16, and EG.5.1, collected after (A) 1 month (median 36 days; left column) and (B) 4 months (median 126 days; right column) post-4th dose with parental ChAdOx1-S vaccine. (B) NT50 values of sera from individuals with infection history were subdivided into two groups: the ones infected before the BA.4/5 wave (mainly during the BA.1/BA.2 wave) and the ones infected during the BA.4/5 wave. Geometric mean titers (GMTs) are noted above the respective groups. Colors designate infection history, data points represent individual subjects, bars represent GMT with 95% confidence intervals (CI) and dotted lines represent the lower limit of detection of NT50 (LOD = 18). Groups were compared by the non-parametric Mann–Whitney test (ns = not significant, * = p < 0.05). Panels (A,B) were generated using GraphPad Prism v10.0 software. See Table S5 for the complete data.