Table 2.

α-Conotoxins identified from predatory and defense venoms of fish-hunting cone snails. Presented here are conotoxins found exclusively in the predation-evoked, the defense-evoked, or in both venoms. Each conotoxin is characterized by its Conus clade, the Conus species in which it was detected, the given name, its sequence, its classification within the gene superfamilies, and the cysteine framework. Cysteine residues are highlighted in red.

Clades	Conus Species	Conotoxins	Mature Sequence	Gene Superfamily	Cysteine Framework	References
Pionoconus	striatus	α-SI	ICCNPACGPKYSCX	A	I	[23,32,39]
		α-SIA	YCCHPACGKNFDCX	A	I	[23,32]
		α-SII	GCCCNPACGPNYGCGTSCS	A	II	[23,32,39]
	consors	α-CnIB	CCHPACGKYYSCX	A	I	[24,37]
		α-CnIA	GRCCHPACGKYYSCX	A	I	[24,37]
		CnIG	CCHPACGKYFKCX		I	[37]
		CnIJ	GRCCHPACGGKYFKCX	A	I	[37]
		CnIH	NGRCCHPACGKHFSCX	A	I	[37]
		CnIK	NGRCCHPACGKYYSCX	A	I	[37]
		CnIL	DGRCCHPACGKYYSCX	A	I	[37]
	catus	α-C4.3	NGRCCHPACGKHFSC	A	I	[25]
		α-CIB	GCCSNPVCHLEHPNACX	A	I	[25]
		α-C1.3	GCCSNPVCHLEHSNLCX	A	I	[25]
	magus	α-MI	GRCCHPACGKNYSCX	A	I	[40]
		α-MII	GCCSNPVCHLEHSNLCX	A	I	[40]
		α-MIC	CCHPACGKNYSCX	A	I	[40]
Gastridium	geographus	α-GIC	GCCSHPACAGNNQHICX	A	I	[28,33]
		α-GIA	ECCHPACGRHYSCGK	A	I	[28,33]
		α-GII	ECCHPACGKHFSCX	A	I	[28,33]
		α-GID	IRD(Gla)CCSNPACRVNNPHVC	A	I	[28,33]
	obscurus	α-OIVA	CCGVONAACHOCVCKNTCX	A	IV	[28,41]
		α-OIVB	CCGVONAACPOCVCNKTCGX	A	IV	[28,42]
Chelyconus	purpurascens	α-PIB	ZSOGCCWNPACVKNRCX	A	I	[17,43]
		α-PIC	SGCCKHOACGKNRC	A	I	[17,44]
		α-PIVA	GCCGSYONAACHOCSCKDROSYCGQX	A	IV	[17]
		α-PIIIE	HOOCCLYGKCRRYPGCSSASCCQRX	M	III	[17]
		α-PIIIF	GOOCCLYGSCROFOGCYNALCCRKX	M	III	[17,45]
	ermineus	α-EIVA	GCCGPYONAACHOCGCKVGROOYCDROSGGX	A	IV	[46,47]
		α-EIVB	GCCGKYONAACHOCGCTVGROOYCDROSGGX	A	IV	[46,47]
		α-EIIA	ZTOGCCWNPACVKNRCX	A	I	[47,48]
		α-EIIB	ZTOGCCWHPACGKNRCX	A	I	[47,48]
		α-EI	RDOCCYHPTCNMSNPQICX	A	I	[47,49]