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. 2024 Feb 7;16(2):94. doi: 10.3390/toxins16020094

Table 5.

ω-Conotoxins identified from predatory and defense venoms of fish-hunting cone snails. Presented here are conotoxins found exclusively in the predation-evoked, the defense-evoked, or in both venoms. Each conotoxin is characterized by its Conus clade, the Conus species in which it was detected, the given name, its sequence, its classification within the gene superfamilies, and the cysteine framework. Cysteine residues are highlighted in red.

Clades Conus Species Conotoxins Mature Sequence Gene
Superfamily
Cysteine Framework References
Pionoconus striatus ω-SVIA CRSSGSOCGVTSICCGRCYRGKCTX O1 VI/VII [39,64]
ω-SVIB CKLKGQSCRKTSYDCCSGSCGRSGKCX O1 VI/VII [39,64]
SO4 ATDCIEAGNYCGPTVMKICCGFCSPYSKICMNYPKN O1 VI/VII [23,32]
SO5 STSCMEAGSYCGSTTRICCGYCAYFGKKCIDYPSN O1 VI/VII [23,32]
consors ω-CnVIIA CKGKGAOCTRL(Mox)YDCCHGSCSSSKGRCX O1 VI/VII [24,37,51]
magus ω-MVIIA CKGKGAKCSRLMYDCCTGSCRSGKCX O1 VI/VII [40]
ω-MVIIB CKGKGASCHRTSYDCCTGSCNRGKCX O1 VI/VII [40]
catus ω-Catus-C2 CQGRGASCRKTMYNCCSGSCNRGRC O1 VI/VII [25]
ω-CVIA CKSTGASCRRTSYDCCTGSCRSGRCX O1 VI/VII [25,61]
ω-CVID CKSKGAKCSKLMYDCCSGSCSGTVGRCX O1 VI/VII [25,61]
Gastridium geographus ω-GVIA CKSOGSSCSOTSYNCCRSCNOYTKRCY O1 VI/VII [28,33]
ω-GVIIA CKSOGTOCSRGMRDCCTSCLLYSNKCRRY O1 VI/VII [28,33]
ω-GVIIB CKSOGTOCSRGMRDCCTSCLSYSNKCRRY O1 VI/VII [28,33]