Table 13.

Conopeptides identified from predatory and defense venoms of mollusc-hunting cone snails. Presented here are conotoxins found exclusively in the predation-evoked, the defense-evoked, or in both venoms. Cysteine residues are highlighted in red. The complete table can be found in the Supplementary Table S1.

Clades	Conus Species	Conotoxin/ Conopeptide	Mature Sequence	Conopeptide Class	Cysteine Framework	References
Conus	marmoreus	χ/λ-CMrVIA	VCCGYKLCHPC		X	[81]
		Contryphan-M2	ESECPWHPWCX	Contryphan		[81]
		ω-Contryphan-M	NESECPWHPWCX	Contryphan		[81]
		Conomarphin-Mr1	DWEYHAHPKPNSFWT	Conomarphin		[81]
		Conomarphin-Mr2	DWVNHAHPQPNSIWS	Conomarphin		[81]
Cylinder	textile	Textile Convulsant Peptide (TCP)	NCPYCVVYCCPPAYCEASGCRPPX		O1	[16]
	victoriae	Elevenin-Vc1	RRIDCKVFVFAPICRGVAA	Elevenin		[21]
		Prohormone-4-Vc1	IGFPGFSTPPR	Prohormone		[21]
		P_088	TTVEKNKPGVLDIPVKSNSDDDSIFRYGRRDMQSPLLSERLRF	Conorfamide		[80]
		P_087	SFGGEHVCWLGDPNHPQGVCGPQVANIVEIRCEEKEAEQGGANNARANTGRTSSLMKRRGFLSLLKKRGKRDEGSPLQRSGRGIVCECCKHHCTKEEFTEYCH	Insulin	XII	[80]
	ammiralis	D_086	HSGILLAWSGPRNRFVRFG	Conorfamide		[80]
		D_002	AQDYSTAELCRINSNDCSVPFSWIPCQQHFLAACDRHDTCYLCGAHFNFTQDDCDNAFLRDMTALCANGTDDEGFCLQ	Conodipine	XXXIII	[80]
		D_030	ASCPENSCDFASPFQCGEMQTCIRLFQVCDGLWHCENGFDEDLAVCAAVLRPLECAIWEFLEEQSDWILPELFNNADSDLVAPVLHGAYSMGDLQSILNLTAQNIENIRNSTRGAIEGDERPLLALGMPEGAWNDVRYLLEELYKLGLDVWTE	Prohormone-4	XXII	[80]
	ammiralis	P_016	INCKVFVYAPICRGVAA	Conoporin		[80]
		P_158	HPTKACMNCTFGQCVGPQVCCGAGGCEMGTAEANRCSEEDEDPIPCLVIGAHCSLNNPGNIHGNCVAHGICCVDDTCAIHFGCL	Conophysin		[80]
			CFIRNCPSGG	Conopressin		[80]