Figure 8.

LA ameliorates dopaminergic neuronal damage and inhibits microglia activation in the brain of Parkinson’s disease mice. (A) In vivo experimental procedure; (B) Changes in body weights of mice; (C) Effect of LA on TH in the substantia nigra and striatum of Parkinson’s model mice; (D) Effect of LA on Iba-1 in the substantia nigra and striatum of Parkinson’s model mice. In the red squares are the microglia, which are magnified; (E) Western blot of TH and Iba-1 expression in the substantia nigra of Parkinson’s model mice. vs. CON, ^# p < 0.05, ^## p < 0.01, vs. MPTP, * p < 0.05, ** p < 0.01. Data are presented as the mean ± SD. LA: Levistilide A, LPS: lipopolysaccharide.