Table 1.
Demographic data, PROMs score evolution and response characteristics in our cohort. Abbreviatures: National Eye Institute Visual Functioning Questionnaire-25 (NEI-VFQ 25), Interquartile range (IQR).
| Total n = 37 |
Poor Responder 12 Months n = 20 (54%) |
Good Responder 12 Months n = 17 (46%) |
p-Value | |
|---|---|---|---|---|
| Sex | Male 14 (38%) | Male 8 (40%) | Male 6 (35%) | 0.776 + |
| Female 23 (62%) | Female 12 (60%) | Female 11 (65%) | ||
| Age | 79.19 (±8.01) | 78.85 (±7.93) | 79.59 (±8.34) | 0.785 + |
| Total NEI-VFQ 25 score at baseline (Mean, SD) | 82.14 (±8.32) | 81.92 (±9.42) | 82.39 (±7.09) | 0.865 + |
| Total NEI-VFQ 25 score at month 4 (Mean, SD) | 85.30 (±7.26) | 85.52 (±7.62) | 85.05 (±7.05) | 0.846 + |
| Total NEI-VFQ 25 score at month 12 (Mean, SD) | 86.41 (±6.51) | 86.31 (±7.04) | 86.52 (±6.03) | 0.924 + |
| Response at month 4 | 0.743 * | |||
| Poor responder (n, %) | 13, 35% | 8, 40% | 6, 35% | |
| Good responder (n, %) | 24, 65% | 12, 60% | 11, 65% | |
| Total injections (Mean, IQR) | 9 (8–10) | 9 (8–10) | 9 (8–9) | 0.059 ‡ |
| Weeks between injection (Mean, IQR) | 8 (6–9) | 7 (6–8) | 9 (7–9) | 0.048 ‡ |
* Tested by Chi2, + Tested by Student-t, ‡ Non-normal distribution (Tested by Shapiro-Wilks test), variable tested by Mann-Whitney test.