Table 2.

Association analysis of mtSNP in AR group and control group

SNP NO	Gene	Region	Rare Allele	FA	FC	OR (95%CI)	p-value	pBH	pB
MT4715.A/G	ND2	Synonymous	G	4/132	24/108	0.1332(0.04467–0.3973)	0.0003	0.0276	0.0276
MT15487.A/T	CYTB	Synonymous	T	4/132	22/110	0.1494(0.04983–0.4477)	0.000687	0.0316	0.0632
MT7196.C/A	COX1	Synonymous	A	4/132	22/110	0.1494(0.04983–0.4477)	0.000687	0.0211	0.0632
MT302.-/CCC	NONE	Intergenic	CCC	34/102	14/118	2.795(1.417–5.516)	0.003037	0.0699	0.2794
MT6962.G/A	COX1	Synonymous	A	18/118	4/128	5.071(1.652–15.56)	0.004547	0.0837	0.4183
MT10609.T/C	ND4L	Nonsynonymous	C	16/120	4/128	4.5(1.442–14.04)	0.009597	0.1472	0.8829
MT12406.G/A	ND5	Nonsynonymous	A	16/120	4/128	4.5(1.442–14.04)	0.009597	0.1261	0.8829
MT12882.C/T	ND5	Synonymous	T	16/120	4/128	4.5(1.442–14.04)	0.009597	0.1104	0.8829
MT16298.T/C	tRNA-Pro	Intergenic	C	8/128	20/112	0.3442(0.1457–0.8133)	0.01506	0.1111	1.0000
MT13759.G/A	ND5	Nonsynonymous	A	12/124	2/130	6.684(1.445–30.92)	0.01507	0.1000	1.0000
MT16311.T/C	tRNA-Pro	Intergenic	C	26/110	12/120	2.478(1.178–5.213)	0.01682	0.0909	1.0000
MT8584.G/A	ATP6	Nonsynonymous	A	14/122	26/106	0.4546(0.225–0.9186)	0.02805	0.0833	1.0000
MT14668.C/T	ND6	Synonymous	T	34/102	20/112	1.925(1.033–3.587)	0.03914	0.0769	1.0000
MT8414.C/T	ATP8	Nonsynonymous	T	34/102	20/112	1.925(1.033–3.587)	0.03914	0.0714	1.0000
MT16260.C/T	tRNA-Pro	Intergenic	T	4/132	12/120	0.2953(0.09186–0.949)	0.04058	0.0667	1.0000
MT10310.G/A	ND3	Synonymous	A	18/118	8/124	2.461(1.015–5.964)	0.04618	0.0625	1.0000
MT6392.T/C	COX1	Synonymous	C	18/118	8/124	2.461(1.015–5.964)	0.04618	0.0588	1.0000

SNP, single nucleotide polymorphism; MT, mitochondrial; FA, frequency of affected; FC, frequency of control; OR, odd ratio. CI, confidence interval;

p_BH, p_{Bonjamini-Hochberg;} p_B, p_Bofferoni