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. 2024 Feb 24;22:29. doi: 10.1186/s12969-024-00960-w

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 3 — Representative eosinophilic fasciitis pathology characteristics. A Hematoxylin and eosin (H&E) section (patient 4, magnification, × 40) showing fascia with underlying muscle. The fascia shows thickening and moderate inflammatory cell infiltration. B H&E section (patient 3, magnification, × 400) showing extensive infiltration of fascia by inflammatory cells composed of lymphocytes, plasma cells, macrophages, and eosinophils. C CD45 (leukocyte common antigen, LCA) immunohistochemical stain (patient 4, magnification, × 200) highlighting the inflammatory cells. D CD163 immunohistochemical stain (patient 4, magnification, × 200) highlights macrophages. E CD138 immunohistochemical stain (patient 4, magnification, × 200), highlights plasma cells. F H&E section (patient 4, magnification, × 200) showing muscle with mild perimysial inflammation (black arrow)