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. 2024 Feb 25;14:4580. doi: 10.1038/s41598-024-54996-9

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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The two-sample t-test results of higher mfALFF in hypertensive patients compared with healthy controls. Higher mfALFF was found in the (a) left superior parietal lobule, (b) left medial frontal gyrus, and (c) right inferior frontal gyrus in the HTN group than in the HC group, with corrected p < 0.02 and cluster size > 50. The two-sample t-test results of lower mfALFF in hypertensive patients compared with healthy controls. Lower mfALFF was found in the HTN group than in the HC group in the (d) right posterior cingulate gyrus, (e) left superior temporal gyrus, and (f) right superior temporal gyrus, with p < 0.02 and cluster size > 100. The color bar indicates the t-score.