Table 2.
New or persistent symptoms at the time of survey completion post-hospital discharge by recovered status. Symptoms are grouped by organ systema.
| Category/symptom, n (%) | Overall N = 79 |
Not recovered N = 23 (29.1%) |
Recovered N = 56 (70.9%) |
P-value* |
|---|---|---|---|---|
| Any symptom | 53 (67.1) | 16 (69.6) | 37 (66.1) | 1.000 |
| Neurologic | 45 (49.5) | 20 (87.0) | 17 (30.4) | <0.001 |
| Headache | 23 (25.4) | 14 (60.9) | 6 (10.8) | <0.001 |
| Weakness | 20 (25.3) | 11 (47.8) | 9 (16.1) | 0.01 |
| Balance problems | 12 (15.2) | 7 (30.4) | 5 (8.9) | 0.03 |
| Loss of smell | 11 (13.9) | 7 (30.4) | 4 (7.1) | 0.01 |
| Loss of taste | 9 (11.4) | 6 (26.1) | 3 (5.4) | 0.02 |
| Tingling sensations | 9 (11.4) | 7 (30.4) | 2 (3.6) | 0.002 |
| Shooting or burning pain | 8 (10.1) | 6 (26.1) | 2 (3.6) | 0.01 |
| Dizziness (room is spinning) | 6 (7.6) | 5 (21.7) | 1 (1.8) | 0.01 |
| Numbness | 5 (6.4) | 5 (21.8) | 0 (0.0) | 0.001 |
| Vision problems | 4 (5.1) | 3 (13.1) | 0 (0.0) | 0.07 |
| Seizures | 4 (5.1) | 1 (4.4) | 3 (5.4) | 1.00 |
| Delirium or confusion | 4 (5.1) | 3 (13.1) | 1 (1.8) | 0.07 |
| Physical | 28 (30.8) | 14 (60.9) | 9 (16.1) | <0.001 |
| Muscle aches or pain | 17 (21.6) | 13 (56.5) | 4 (7.1) | <0.001 |
| Joint pain | 14 (17.7) | 9 (38.1) | 5 (8.9) | 0.003 |
| Swallowing/chewing problem | 6 (7.6) | 3 (13.1) | 3 (5.4) | 0.35 |
| Cognitive | 20 (22.0) | 11 (47.8) | 4 (7.1) | <0.001 |
| Thinking or concentration problem | 10 (12.7) | 8 (34.8) | 2 (3.6) | 0.001 |
| Trouble with remembering things | 9 (11.4) | 8 (34.7) | 1 (1.8) | <0.001 |
| Speaking/communicating problem | 7 (8.9) | 5 (21.8) | 2 (3.6) | 0.02 |
| Emotional | 25 (27.5) | 13 (56.5) | 7 (12.5) | |
| Anxious | 19 (24.1) | 12 (52.1) | 7 (12.5) | <0.001 |
| Sad or depressed | 11 (14.0) | 7 (30.4) | 4 (7.1) | 0.01 |
| General | 41 (45.1) | 15 (65.2) | 20 (35.7) | 0.02 |
| Fatigue or tiredness | 31 (39.3) | 14 (60.9) | 17 (30.4) | 0.02 |
| Fever | 17 (21.5) | 8 (34.8) | 9 (16.1) | 0.08 |
| Loss of appetite | 15 (19.0) | 7 (30.5) | 8 (14.3) | 0.12 |
| Sleep problems | 14 (17.7) | 9 (39.1) | 5 (8.9) | 0.003 |
| Throat pain | 9 (11.4) | 6 (26.1) | 3 (5.4) | 0.02 |
| Swollen glands | 3 (3.8) | 3 (13.1) | 0 (0.0) | 0.02 |
| Respiratory | 27 (29.7) | 9 (39.1) | 13 (23.2) | 0.17 |
| Cough | 18 (22.8) | 9 (39.1) | 9 (16.1) | 0.04 |
| Trouble breathing | 15 (19.0) | 8 (34.8) | 7 (12.5) | 0.03 |
| Gastrointestinal | 28 (30.8) | 13 (56.5) | 10 (17.9) | 0.00 |
| Abdominal pain | 16 (20.3) | 9 (39.1) | 7 (12.5) | 0.01 |
| Diarrhea | 15 (19.0) | 8 (34.7) | 7 (12.5) | 0.03 |
| Vomiting or nausea | 13 (16.4) | 8 (34.8) | 5 (8.9) | 0.01 |
| Cardiovascular | 21 (23.1) | 10 (43.5) | 5 (8.9) | 0.01 |
| Palpitations | 10 (12.7) | 7 (30.5) | 3 (5.4) | 0.01 |
| Lightheadedness or fainting | 8 (10.1) | 6 (26.0) | 2 (3.6) | 0.01 |
a
From the Case Report Form: “For each of the symptoms listed below, please answer whether your child had any new or continuing symptoms after the hospitalization that included a COVID-19 or MIS-C diagnosis. You can type in other symptoms at the bottom of this section”.
*
p-value for any symptom (new or persistent) vs. none.
**
Combined for analysis.
***
Combined with No for analysis.