Table 2.

Functional studies at baseline and at diagnosis of ACC.

	2009			2017
	Ur vol (L)	Value	RR	Ur vol (L)	Value	RR
24-h urine studies
Cortisol (nmol/day)	2.53	104	70–430	1.69	237	54–319
Metanephrines (µmol/day)	3.01	0.6	< 2.1	1.23	0.4	< 0.4
Normetanephrines (µmol/day)	3.01	2.5	< 5.1	1.23	2.4	< 2.3
Plasma studies
Aldosterone (pmol/L)		–			489	100–950
Renin (mU/L)		–			206	3.3–41
ARR		–			2	< 70

Baseline aldosterone and renin were not measured as patient was on medications that interfered with testing.

ACC, adrenal cortical carcinoma; ARR, aldosterone-to-renin ratio; RR, reference range; Ur vol, urine volume.