TABLE 2.
Cell line | Doubling time (h) in medium
|
|
---|---|---|
3H (+TSH) | 2H (−TSH) | |
WRT | 34.2 ± 2.4 | 62.7 ± 3.6 |
RasV12 | 36.7 ± 1.9 | 26.6 ± 2.7 |
RasS35 | 37.2 ± 4.1 | 32.0 ± 6.2 |
RasG37 | 27.5 ± 2.3 | 35.7 ± 3.3 |
The P value for the RasG37 trials was <0.025, while the P value for the RasV12 trials was <0.005. The effects of TSH on growth rate in RasS35 cells were not statistically significant although they were consistently observed. The results shown are representative of four independent experiments performed with similar results.