TABLE 3.

Correlations with caspase-1

Caspase-1	Healthy controls	ICU-non-sepsis	ICU-sepsis	All patients
IL-18	ns	r=0.41# p=0.0135 n=36	r=0.39 p=0.0004 n=76	r=0.43 p<0.0001 n=149
Aβx-40	ns	ns	r=0.32 p=0.0051 n=74	r=0.36 p<0.0001 n=163

Correlations were drawn between all patients and within each of the three groups utilising Pearson's correlation. Correlations are shown as Pearson's r, followed by t-test p-value below, and number of pairs of observations (n). r>0.3 and p<0.05 were considered significant. ICU: intensive care unit; IL-18: interleukin-18; ns: nonsignificant. ^#: patient plasma samples were categorised as healthy, ICU-non-sepsis or ICU-sepsis patients.