Table 3.
Outcomes of ART treatment.
| rFSH-alfa (n=375) |
HP-hMG (n=105) |
uFSH (n=173) |
rFSH-beta (n=118) |
P-value | ||
|---|---|---|---|---|---|---|
| ART method [n (%)] | 0.012 | |||||
| IVF | 310 (82.7) | 92 (87.6) | 148 (85.5) | 102 (86.4) | ||
| ICSI | 17 (4.5) | 11 (10.5) | 10 (5.8) | 5 (4.2) | ||
| IVF+ICSI | 48 (12.8) | 2 (1.9) * | 15 (8.7) | 11 (9.3) | ||
| Normal fertilized rate [n(%)] | 4120/6652 (61.9) | 787/1243 (63.3) | 1464/2582 (56.7) *† | 1153/1948 (59.1) | <0.001 | |
| No. of high-quality D3 embryos | 4.0 (2.0-7.2) | 4.0 (2.0-6.0) | 3.0 (1.0-5.0) * | 4.5 (2.0-7.0) ‡ | <0.001 | |
| High-quality D3 embryos rate [n(%)] | 1971/4120 (47.8) | 426/787 (54.1) * | 669/1464 (45.7) † | 582/1153 (50.5) | 0.001 | |
| No. of available D3 embryos | 9.0 (6.0-13.0) | 7.0 (6.0-9.0) * | 6.0 (4.0-10.0) * | 8.0 (5.0-12.0) | <0.001 | |
| Available D3 embryos rate [n(%)] | 3820/4120 (92.7) | 775/787 (98.5) * | 1339/1464 (91.5) † | 1079/1153 (93.6) † | <0.001 | |
| High-quality blastocysts rate [n(%)] | 679/2199 (30.9) | 190/447 (42.5) * | 195/658 (29.6) † | 151/598 (25.3) *† | <0.001 | |
| Available blastocysts rate [n(%)] | 1509/2199 (68.6) | 426/447 (95.3) * | 480/658 (72.9) † | 505/598 (84.4) *†‡ | <0.001 | |
| Fresh ET cancellation rate [n(%)] | 288 (76.8) | 54 (51.4) * | 101 (58.4) * | 85 (72.0) † | <0.001 | |
| Clinical pregnancy rate [n(%)] | 50/87 (57.5) | 32/51 (62.7) | 38/72 (52.8) | 15/33 (45.5) | 0.426 | |
Data are presented as median (25th-75th percentiles) or number (percentage).
*p<0.05 compared to rFSHα group; †p<0.05 compared to HP-hMG group; ‡p<0.05 compared to uFSH group.
ART, assisted reproductive technology; IVF, in vitro fertilization; ICSI, intracytoplasmic sperm injection; D3, day 3.