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In vivo evaluation of 31c in a stage-I mouse model of HAT. Parasitemia (A) and survival rate (B) of stage-I T. b. brucei-infected mice treated with vehicle (n = 3), suramin (n = 3) at 10 mg/kg or 31c (n = 3) at 50 or 25 mg/kg. Results in figure A are expressed as mean number of bloodstream forms (BSF)/mL ± standard error of mean (SEM). VIC, vehicle.
