Fig. 7.

Treatment recommendations for Rett syndrome. N = 13 (13 positive and 0 negative recommendations) from three guidelines. Positive recommendation: use of an individual ASM treatment that was recommended for use in a specific indication, irrespective of the line of treatment (e.g. first line) or whether the treatment was adjunctive; Negative recommendation: an individual ASM treatment that was highlighted as a potential option by a guideline but not recommended by a guideline for use (for any reason) in a specific indication, irrespective of the line of treatment or whether the treatment was adjunctive