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. Author manuscript; available in PMC: 2024 Nov 22.
Published in final edited form as: Cell. 2023 Nov 22;186(24):5269–5289.e22. doi: 10.1016/j.cell.2023.10.023

Figure 4. Higher-order chromatin compartmentalization is controlled by IKAROS.

Figure 4.

(A) Bins with different compartment affiliation scores between IKDN and WT classified by affiliation shift. (B) Distributions of differential compartmental bins with (colored) or without (black outline) overlap with differential loop anchors identified by indicated HiChIP and numbers are shown. (C) Differential H3K27ac regulatory loops classified in WT as intra-compartmental, inter-compartmental and consecutive. (D) Examples of compartmental changes associated with intra-(left) and inter-(right) compartmental regulatory loops downregulated in IKDN. Source: Tables S2-3, S6.