Table 2.

Treatment Preference results from the DCE, Overall and Stratified by Diabetes Status and Toenail Onychomycosis Severity

	Overall	p-value	Diabetes Status				Toenail Onychomycosis Severity
			No		Yes		Mild/ Moderate		Severe
	n=309		n=149		n=160		n=111		n=188
	OR (95% CI)		OR (95% CI)	p-value	OR (95% CI)	p-value	OR (95% CI)	p-value	OR (95% CI)	p-value
Efficacy
Efficacy*	1.04 (1.02, 1.05)	<0.01	1.01 (0.99, 1.03)	0.37	1.06 (1.04, 1.08)	<0.01	1.02 (0.99, 1.05)	0.13	1.05 (1.02, 1.07)	<0.01
Treatments
One pill**	1.14 (1.04, 1.26)	0.01	1.16 (1.01, 1.34)	0.03	1.12 (0.98, 1.29)	0.10	1.16 (0.99, 1.35)	0.07	1.13 (1.00, 1.28)	0.05
Topical applicator**	1.15 (1.03, 1.29)	0.01	1.28 (1.09, 1.50)	<0.01	1.05 (0.90, 1.23)	0.55	1.12 (0.94, 1.35)	0.20	1.17 (1.02, 1.36)	0.03
Two pills**	1.03 (0.94, 1.14)	0.51	1.08 (0.94, 1.24)	0.27	0.99 (0.86, 1.14)	0.88	0.93 (0.80, 1.09)	0.37	1.11 (0.98, 1.26)	0.11
Adverse events
Mild adverse events*	1.00 (0.99, 1.00)	0.13	1.00 (1.00, 1.00)	0.80	1.00 (0.99, 1.00)	0.06	1.00 (0.99, 1.00)	0.36	1.00 (0.99, 1.00)	0.22
Severe adverse events*	0.85 (0.80, 0.90)	<0.01	0.88 (0.81, 0.95)	<0.01	0.82 (0.76, 0.89)	<0.01	0.87 (0.79, 0.95)	<0.01	0.84 (0.78, 0.90)	<0.01
Interactions
Medication interactions	0.80 (0.76, 0.85)	<0.01	0.86 (0.79, 0.93)	<0.01	0.76 (0.70, 0.82)	<0.01	0.78 (0.72, 0.86)	<0.01	0.82 (0.76, 0.88)	<0.01
Alcohol interactions	0.93 (0.88, 0.98)	0.01	1.04 (0.96, 1.13)	0.36	0.83 (0.77, 0.90)	<0.01	0.92 (0.84, 1.01)	0.08	0.93 (0.86, 1.00)	0.04

Notes: *Per 1% increase; **Topical nail lacquer was selected as the reference treatment, ie, the treatment against which other treatments were compared; statistically significant p-values (<0.05) are bold.

Abbreviations: CI, confidence interval; OR, odds ratio.