Skip to main content
. Author manuscript; available in PMC: 2024 Feb 26.
Published in final edited form as: J Nutr Biochem. 2023 Jun 10;119:109398. doi: 10.1016/j.jnutbio.2023.109398

Table 1.

Top 10 enrichment terms of GO (biological process) and KEGG pathway for the DEGs induced by HFD in BXD RI mice.

Term Description N. Genes FDR
GO (Biological Process)
GO:0002376 immune system process 444 < 2.06E-14
GO:0002682 regulation of immune system process 239 < 2.06E-14
GO:0006082 organic acid metabolic process 254 < 2.06E-14
GO:0006518 peptide metabolic process 174 < 2.06E-14
GO:0006629 lipid metabolic process 321 < 2.06E-14
GO:0006631 fatty acid metabolic process 113 < 2.06E-14
GO:0006915 apoptotic process 362 < 2.06E-14
GO:0006952 defense response 268 < 2.06E-14
GO:0006955 immune response 255 < 2.06E-14
GO:0008219 cell death 384 < 2.06E-14
KEGG pathway
mmu01100 Metabolic pathways 345 2.03E-11
mmu03010 Ribosome 60 6.65E-09
mmu04142 Lysosome 49 4.93E-06
mmu05204 Chemical carcinogenesis 39 1.36E-05
mmu00260 Glycine, serine and threonine metabolism 20 4.58E-04
mmu04210 Apoptosis 47 6.27E-04
mmu00140 Steroid hormone biosynthesis 33 8.87E-04
mmu00830 Retinol metabolism 33 1.34E-03
mmu00980 Metabolism of xenobiotics by cytochrome P450 26 1.79E-03
mmu05150 Staphylococcus aureus infection 22 2.04E-03