Simulation results depicting the change in QRS duration (A), LV 95% activation time (B), 90% BiV activation time (C), BiV dyssynchronous index (D), and RV latest activation time. Abbreviations: left ventricle (LV), biventricular (BiV), epicardial (epi), endocardial (endo), lateral (lat), septal (sept), selective (S), non- selective (NS), His bundle pacing (HBP), left bundle pacing (LBP), QRS duration (QRSd), 95% LV activation time (LVAT-95), 90% biventricular activation time (BIVAT-90), biventricular dyssynchronous index (BIV DI), right ventricular latest activation time (RV LAT). Reprinted with permission from Strocchi et al. [39].