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. 2024 Feb 26;19(2):e0297080. doi: 10.1371/journal.pone.0297080

Table 1. Shift in ratio of ERα:ERβ in the presence of combined nutraceuticals.

Percentage change in ERα:ERβ compared to the vehicle control when cells were treated for 48 hours with the combined extracts. The total amount of ERα & ERβ staining was quantified from randomly selected microscopic fields (n = 5) and calculated as total staining present per nuclei. EXT1 = All extracts combined except AC, EXT2 = All extracts combined except C.

Percentage Reduction in ERα: ERβ MCF7 T47D BT483
EXT 1 10% 75.9% 129.1% 49.2%
EXT 1 1% 66.7% 80.2% 159.6%
EXT 2 10% 82.4% -29.9% 54.0%
EXT 2 1% 72.8% -49.9% 51.2%