Table 2. Joinpoint analysis for cardiovascular diseases (ICD- 10 I00-I99), according to sex and region. North America, Latin America and Non-Latin Caribbean, 2000-LA.

	Years		AAPC [Confidence Interval]
	Lower Endpoint	Upper Endpoint
Total
North America	2000	2009	-3.9* [-4.2; -3.7]
Latin America	2000	2009	-1.8* [-2.2; -1.5]
Non-Latin Caribbean	2004	2008	-1.8* [-2.7; -0.9]
Female
North America	2000	2009	-4.3* [-4.5; -4.0]
Latin America	2000	2009	-2.0* [-2.4; -1.6]
Non-Latin Caribbean	2004	2008	-1.8* [-3.0; -0.7]
Male
North America	2000	2009	-3.7* [-3.9; -3.4]
Latin America	2000	2009	-1.6* [-2.0; -1.3]
Non-Latin Caribbean	2004	2008	-1.8* [-2.6; -1.0]

^LAY = last available year

^*The AAPC (average annual percentage change) is significantly different from "zero" at alpha = 0.05