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Specific OTUs are associated with ASUC at first presentation. Differentially abundant OTUs [99% clustering] present more than 10 times in at least 20% of samples were determined using ANCOM-BC. Negative log fold change values indicate OTUs enriched in ASUC patients and positive log fold change values indicate OTUs enriched in mild UC. OTU, operational taxonomic units; ASUC, acute, severe ulcerative colitis.
