Table 3.

Unadjusted and adjusted hazard ratio for infliximab initiation within 18 months from presentation with ASUC.

	Unadjusted hazard ratio [95% CI]	p-value	Adjusted hazard ratio [95% CI]†	p-value
Age [years]	1.08 [1.00-1.16]	0.03	1.08 [1.01-1.16]	0.03
Male	1.56 [1.01-2.42]	0.048	1.66 [1.06-2.60]	0.03
PUCAI*	1.04 [1.00-1.07]	0.02	1.04 [1.01-1.08]	0.013
Albumin* g/L	0.93 [0.89-0.96]	<0.001	0.93 [0.89-0.97]	<0.001
CRP* mg/L	1.00 [0.99-1.01]	0.18	-	-
Hb* g/L	1.00 [0.99-1.01]	0.84	-	-
Severe endoscopic disease*	1.32 [0.84-2.09]	0.23	-	-

PUCAI, Paediatric Ulcerative Colitis Activity Index;CRP, C-reactive protein; Hb, haemoglobin.

*Measured at diagnosis.

†Applying backward elimination stepwise regression. Variance inflation factor <1.5 for all variables included in the multivariable model.