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In Vivo Pharmacokinetic Properties of Compound 5d
| PK parameter |
route of dosing |
|
|---|---|---|
| i.v. (n = 3) | p.o. (n = 3) | |
| dose (mg/kg) | 2.00 | 10.00 |
| AUC0–t (h·ng/mL) | 550.95 | 626.55 |
| Cmax (ng/mL) | 1984.94 | 1241.79 |
| Tmax (h) | 0.08 | 0.25 |
| CL ((mL/min)/kg) | 60.5 | |
| Vss (L/kg) | 0.69 | |
| t1/2 (h) | 0.16 | 1.99 |
| F (%) | 22.81 | |
