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Infarct size, expressed as % of left ventricular circumference, was comparable between air or E-cig group after 12 weeks of exposure. The infarct size varied from 29.2% to 71.0% in the air group, and from 17.9% to 64.7% in the E-cig group. The inherent variability of infarction size of in rat model is caused by the facts of the incapacity of occluding the left coronary artery exactly at the same point in all rats, as well as the anatomic variations of coronary artery among the rats
