Table 2.

Characteristics of studies used in the diagnostic accuracy meta-analysis.

Study	CU sample size	CU age	aMCI sample size	aMCI age	AUC ± SE	Cutoff score
Ahmed et al. (2012)	20	77.4 ± 4.0	15	80.9 ± 7.2	0.89 ± 0.05	23
Cecato et al. (2017)	39	71.6 ± 6.9	44	76.7 ± 7.0	0.93 ± 0.03	24
Clarnette et al. (2017)	41	nr	72	nr	0.94 ± 0.02	23
Cummings-Vaughn et al. (2014)	51	77 ± 7.5	57	78.8 ± 6.7	0.77 ± 0.05	24
Dautzenberg et al. (2020)	459	71.3 ± 7.3	153	73.9 ± 8	0.70 ± 0.02	21
Delgado et al. (2019)	104	72.3 ± 5.4	24	75.3 ± 7.8	0.90 ± 0.03	21
Dong et al. (2013)	128	67.4 ± 4.8	83	74.3 ± 5.5	0.94 ± 0.02	24
Freitas et al. (2013)	90	69.6 ± 7.1	90	70.5 ± 8.0	0.86 ± 0.01	22
Fujiwara et al. (2010)	36	76.4 ± 3.3	30	77.3 ± 6.3	0.95 ± 0.03	25
Goldstein et al. (2014)	16	65.8 ± 7.7	38	71.9 ± 8.9	0.81 ± 0.06	24
Hemrungrojn et al. (2021)	60	67.9 ± 6.4	61	72.1 ± 7.0	0.81 ± 0.04	24
Julayanont et al. (2015)	43	66.6 ± 6.7	42	70.2 ± 6.6	0.90 ± 0.03	25
Kaya et al. (2014)	246	68.0 ± 10.3	114	74.2 ± 8.8	0.85 ± 0.02	nr
Larner (2012)	85	nr	29	nr	0.91 ± 0.02	20
Lee et al. (2018)	35	73.6 ± 6.4	36	76.2 ± 7.4	0.94 ± 0.03	nr
Li et al. (2018)	53	70.2 ± 9.1	56	75.2 ± 7.1	0.82 ± 0.07	24
Liew et al. (2015)	146	64.9 ± 7.0	41	71.8 ± 6.7	0.77 ± 0.05	25
Liu et al. (2021)	50	68.0 ± 8.2	50	76.7 ± 10.8	0.74 ± 0.05	23
Lu et al. (2011)	6,283	72.0	1,687	75.1	0.90 ± 0.005	25
Malek-Ahmadi et al. (2014)	73	82.6 ± 7.7	39	80.5 ± 8.4	0.71 ± 0.05	nr
Masika et al. (2021)	19	69.3 ± 5.8	42	70.4 ± 8.0	0.69 ± 0.07	19
Mellor et al. (2016)	708	72.5 ± 8.4	267	76.5 ± 7.7	0.90 ± 0.01	24
Memória et al. (2013)	28	72.5 ± 5.3	30	74.7 ± 5.7	0.82 ± 0.06	nr
Ng et al. (2015)	88	nr	46	nr	0.50 ± 0.05	nr
O’Caoimh et al. (2016)	101	nr	103	nr	0.84 ± 0.06	24
Pan et al. (2022)	431	66.5 ± 9.3	285	72.1 ± 10.5	0.92 ± 0.01	23
Paterson et al. (2022)	40	74.0 ± 7.0	51	75.0 ± 5.7	0.71 ± 0.05	nr
Peixoto et al. (2018)	30	68.6 ± 6.2	30	67.2 ± 9.3	0.78 ± 0.05	22
Pinto et al. (2019a,b)	110	nr	88	nr	0.95 ± 0.02	nr
Roalf et al. (2013)	140	71.2 ± 9.2	126	72.3 ± 8.1	0.73 ± 0.06	nr
Rodríguez-Salgado et al. (2021)	53	70.4 ± 5.9	46	72.7 ± 7.5	0.73 ± 0.06	nr
Rossetti et al. (2019)	45	62.3 ± 6.8	90	64.8 ± 5.9	0.83 ± 0.04	24
Senda et al. (2020)	50	64.9 ± 12.0	94	73.5 ± 8.3	0.83 ± 0.04	nr
Serrano et al. (2020)	155	71.5 ± 6.2	158	72.6 ± 6.3	0.88 ± 0.02	25
Thomann et al. (2020)	283	73.8 ± 5.2	159	76.0 ± 6.0	0.86 ± 0.01	25
Townley et al. (2019)	313	81.7 ± 5.0	114	84 ± 5.2	0.85 ± 0.02	24
Tsai et al. (2016)	26	nr	59	nr	0.91 ± 0.03	27
Yeung et al. (2014)	49	73.6 ± 7.6	49	76.5 ± 7.5	0.84 ± 0.04	21
Yu et al. (2012)	865	70.4 ± 7.1	115	71.5 ± 7.3	0.71 ± 0.02	21
Zhou et al. (2014)	148	67.7 ± 7.2	24	67.2 ± 6.6	0.72 ± 0.10	26

CU, cognitively unimpaired; MCI, mild cognitive impairment; AUC, area under the curve; SE, standard error; nr, not reported.