Table 6.

Multivariable logistic regression analyses assessing the associations of (delta) CRP, (delta) leucocytes and MEWS, measured on POD 1, 2 or 3, with major postoperative complications

	POD 1			POD 2			POD 3
	OR	95% CI	p	OR	95% CI	p	OR	95% CI	p
CRP	1.01	1–1.01	0.03	1.01	1–1.01	0.03	1.01	1.01–1.012	< 0.001
Δ CRP1	N/A	N/A	N/A	1.01	1.01–1.02	< 0.001	1.01	1.01–1.02	< 0.001
Leucocytes	0.96	0.89–1.03	0.26	1.00	0.92–1.09	0.98	1.11	1.04–1.19	0.003
Δ Leucocytes2	N/A	N/A	N/A	1.27	1.13–1.43	< 0.001	1.03	0.92–1.15	0.62
MEWS	1.10	0.78–1.54	0.59	1.21	1.03–1.42	0.02	1.20	0.99–1.44	0.06

¹Delta CRP on POD 2 equals CRP on POD 2 minus CRP on POD 1

Delta CRP on POD 3 equals CRP on POD 3 minus CRP on POD 2

²Delta leucocytes on POD 2 equals leucocytes on POD 2 minus leucocytes on POD 1

Delta leucocytes on POD 3 equals leucocytes on POD 3 minus leucocytes on POD 2

CI confidence interval, CRP C-reactive protein, POD postoperative day, N/A not applicable

Depicting the primary model, with correction for sex, age, stage of disease, BMI, diabetes mellitus and active smoking. Statistically significant results were defined as p ≤ 0.05 and are printed in bold