Table 5.
Multivariable-adjusted OR (95% CI) of psoriasis according to subgroups of SII levels stratified by SIRI levels (103 cells/μL).
| SII levels | p-value for trend | ||||
|---|---|---|---|---|---|
| geometric mean ± SD | Low (Q1-Q3, <549.50) | Medium (Q4, 549.50-737.69) | High (Q5, ≥737.69) | ||
| SIRI levels | |||||
| Low (Q1-Q3, <1.18) | 384.14 ± 2.90 | Ref. | 1.14 (0.72, 1.83) | 1.16 (0.59, 2.29) | 0.540 |
| Medium (Q4, 1.18-1.65) | 585.59 ± 5.09 | Ref. | 1.32 (0.74, 2.34) | 2.17 (1.25, 3.79)** | 0.008 |
| High (Q5, ≥1.65) | 834.97 ± 8.09 | Ref. | 1.26 (0.59, 2.67) | 1.07 (0.60, 1.92) | 0.910 |
ORs were estimated using multivariate logistic regression models and were weight adjusted using NHANES-specified sampling weights. ORs were adjusted for gender, age, race/ethnicity, education levels, marital status, BMI, alcohol intake, serum cotinine, family PIR, hypertension, type 2 diabetes, and hypercholesterolemia. **p<0.01. BMI, body mass index; CI, confidence interval; NHANES, National Health and Nutrition Examination Survey; OR, odds ratio; PIR, poverty income ratio; Ref, reference; SII, systemic immune–inflammation index; SIRI, systemic inflammation response index.