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. 2024 Feb 13;15:1353908. doi: 10.3389/fgene.2024.1353908

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Copyright © 2024 Qian, Huang, Zhang, Yang, Fang, Zhang and Zhang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Sensitivity analysis for significant metabolites on outcome phenotypes. (A) Sensitivity analysis for the significant MR association between PAD and kynurenine. (B) Sensitivity analysis for the significant MR association between appendicular lean mass and pentadecanoate (15:0). (C) Sensitivity analysis for the significant MR association between appendicular lean mass and 1-arachidonoylglycerophosphocholine*. (D) Sensitivity analysis for the significant MR association between appendicular lean mass and androsterone sulfate. (E) Sensitivity analysis for the significant MR association between low hand grip strength and glycine. (F) Sensitivity analysis for the significant MR association between atherosclerosis and mannose. (G) Sensitivity analysis for the significant MR association between atherosclerosis and kynurenine.