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. 2024 Feb 27;8:33. doi: 10.1186/s41747-024-00421-9

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — a Slice-wise evaluation of performance metrics in MNI Talairach ICBM 152 2009c nonlinear symmetric template (MNI152) coordinate system. The graph represents the error distribution per slice between non-contrast-enhanced (CE) manual segmentations (MSegs)—fluid-attenuated inversion-recovery (FLAIR) in red, T1-weighted (T1w) in blue—and the reference CE-T1w computed axial-wise along the z-coordinate (on the left) and coronal-wise along the y-coordinate (on the right) of the MNI152 coordinate system. The vertical green lines highlight three representative axial (z = -12: temporal horn near the head of the hippocampus; z = 10: atrium of the lateral ventricle; z = 18: body of the lateral ventricles near the fornix) and coronal (y = -35: anterior portion of the atrium of the lateral ventricles; y = -42: posterior portion of the atrium of the lateral ventricles; y = -7: anterior portion of the fornix) slices reported in b. b Probability frequency maps of MSegs overlapped to the MNI Talairach ICBM 152 2009c nonlinear symmetric template (MNI152). From left to right, three axial views (z = -12: temporal horn near the head of the hippocampus; z = 10: atrium of the lateral ventricle; z = 18: body of the lateral ventricles near the fornix) and three coronal views (y = -35: anterior portion of the atrium of the lateral ventricles; y = -42: posterior portion of the atrium of the lateral ventricles; y = -7: anterior portion of the fornix). Reported coordinates are centered at the origin of the MNI space. The first row represents the frequency map of the CE-T1w MSeg for representative slices overlapped to the MNI152 template. The second and third rows show the difference between the frequency map of MSegs depicted on non-CE sequences (T1w and FLAIR) and the MSeg obtained from the CE-T1w sequence overlapped to the MNI152, respectively