Table 1.

Results and formulations of quantitative contrast metrics and quantitative segmentation metrics

Metrics	T1w	CE-T1w	FLAIR
Quantitative contrast metrics
Signal-to-noise ratio $\frac{mean\left(R,O,I_{\mathit{values}}\right)}{std\left(b,a,c,k,g,r,o,u,n,d_{\mathit{values}}\right)}$	13.73 ± 4.89	23.77 ± 12.02	13.09 ± 6.15
Contrast-to-noise ratio $\frac{mean\left(R,O,I_{\mathit{values}}\right)-mean\left(b,a,c,k,g,r,o,u,n,d_{\mathit{values}}\right)}{std\left(b,a,c,k,g,r,o,u,n,d_{\mathit{values}}\right)}$	7.44 ± 2.87	18.49 ± 9.57	10.77 ± 5.38
Quantitative segmentation metrics
Dice similarity coefficient $\frac{2*TP}{2*TP+FP+FN}$	0.67 ± 0.05	-	0.68 ± 0.05
Absolute volume [mL]	3.073 ± 0.563 mL	2.984 ± 0.506 mL	3.787 ± 0.679 mL
Percentage volume difference $100*\frac{\left(V,o,l,u,m,e_{\mathit{segm}},-,V,o,l,u,m,e_{\mathit{ref}}\right)}{Volum{e}_{\mathit{ref}}}\left[\%\right]$	3.52 ± 12.61	-	28.02 ± 19.02
Absolute percentage volume difference $100*\frac{\mid Volum{e}_{\mathit{segm}}-Volum{e}_{\mathit{ref}}\mid }{Volum{e}_{\mathit{ref}}}\left[\%\right]$	10.57 ± 7.60	-	28.43 ± 18.40
Pearson’ correlation	0.77	-	0.67
Spatial variability metrics
Error distribution per slice	$100*\frac{\left(V,o,x,e,l,S,l,i,c,e,{(i)}_{\mathit{segm}},-,V,o,x,e,l,S,l,i,c,e,{(i)}_{\mathit{ref}}\right)}{Volum{e}_{\mathit{ref}}}\left[\%\right]$

Data are presented as mean ± standard deviation. Quantitative contrast metrics: contrast-to-noise ratio and signal-to-noise ratio between choroid plexus (ChP) manual segmentation (MSeg) obtained from each sequence and a reference region obtained excluding the ChP from the ventricles (for details, see the “Quantitative contrast metrics” section). Quantitative segmentation metrics: Dice similarity coefficient, absolute volume, absolute percentage volume difference, and Pearson volume correlation analysis between MSegs obtained from non-contrast enhanced sequences (T1w and FLAIR MSeg) and the reference contrast-enhanced T1-weighted MSeg. FN, False negative; FP, False positive; TP, True positive