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. 2024 Jan 8;25(2):832–852. doi: 10.1038/s44319-023-00033-1

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. Creative Commons Public Domain Dedication waiver http://creativecommons.org/publicdomain/zero/1.0/ applies to the data associated with this article, unless otherwise stated in a credit line to the data, but does not extend to the graphical or creative elements of illustrations, charts, or figures. This waiver removes legal barriers to the re-use and mining of research data. According to standard scholarly practice, it is recommended to provide appropriate citation and attribution whenever technically possible.

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Figure EV4 — (A) GO enrichment histogram showing significantly enriched biological processes upon BRD4-L and BRD4-S knockdown based on the number of differentially expressed genes. (B) RT-qPCR analysis of MSTN, MYL12A and MYL5 mRNA in siScr, siBRD4-L and siBRD4-S cells. The values correspond to average ± SEM (n = 4 biological replicates). n.s. = not significant, ***p ≤ 0.001, n.s. not significant. (C) RT-qPCR analysis of the integrin (ITGA1, ITGA3, ITGA4 and ITGA5) mRNA in siScr, siBRD4-L and siBRD4-S cells. The values correspond to average ± SEM (n = 4 biological replicates). Two-tailed non-parametric unpaired t test was performed for statistical analysis. n.s. not significant, ***p ≤ 0.001, n.s. not significant.