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. 2024 Jan 15;43(3):391–413. doi: 10.1038/s44318-024-00027-2

Figure 5. Defects to mitochondrial functions are observed in cells with altered Opa1 levels.

Figure 5

(A) OCR plotted against time with the addition of each compound indicated by an arrow for oligomycin (2 µM), FCCP (1 µM), and rotenone/antimycin A (0.5 µM). Error bars represent SD from N = 3 biological replicates. (B) Aspects of mitochondrial respiration; basal respiration rates, the amount of respiration used for ATP production, maximum respiration and spare capacity, are extracted by the data plotted in (A). Error bars represent range for N = 3 biological replicates. Data Information: Significance of difference is tested relative to WT using Welch’s t test; *p < 0.05, **p < 0.01. Source data are available online for this figure.