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. 2024 Feb 26;14:4643. doi: 10.1038/s41598-024-54452-8

Table 3.

Differences between nerve and fascicle cross-sectional area (in mm2) for median and ulnar nerve in controls and patients with immune neuropathies.

Control anti-MAG CIDP d-CIDP p
MN n-CSA wrist 10.14 ± 1.42 11.77 ± 2.67 12.80 ± 3.00 10.92 ± 2.07 0.093
MN n-CSA mid-forearm* 7.25, (IQR 6.2–7.7) 10.51, (IQR 9.9–11.2) 9.03, (IQR 7.6–13.6) 11 (IQR 7–11.8) 0.009
MN n-CSA antecubital fossa 12.50 ± 2.55 16.87 ± 6.14 16.29 ± 5.49 11.99 ± 3.70 0.084
MN n-CSA mid-arm* 11.05 ± 0.99 15.94 ± 3.93 17.30 ± 6.10 12.26 ± 5.70 0.003
MN f-CSA wrist 0.78 ± 0.30 0.92 ± 0.29 1.04 ± 0.41 0.84 ± 0.46 0.339
MN f-CSA mid-forearm* 0.76 ± 0.22 1.06 ± 0.57 1.47 ± 0.69 1.27 ± 0.56 0.021
MN f-CSA antecubital fossa* 1.59 ± 1.04 1.79 ± 0.71 4.84 ± 3.16 4.37 ± 2.07 0.007
MN f-CSA mid-arm* 1.53 ± 0.78 2.80 ± 1.15 5.04 ± 3.09 4.98 ± 1.82  < 0.003
UN n-CSA Guyon 6.10, (IQR 5.4–6.4) 6.61, (IQR 5.4–6.9) 6.48, (IQR 5.8–9.7) 6.95, (IQR 5.1–7.6) 0.347
UN n-CSA mid-forearm* 6.04 ± 1.08 7.83 ± 1.48 8.53 ± 2.94 5.94 ± 0.98 0.012
UN n-CSA below elbow* 7.89 ± 0.89 10.63 ± 3.60 11.10 ± 3.01 8.56 ± 2.64 0.040
UN n-CSA elbow* 9.49 ± 1.76 15.33 ± 4.26 11.00 ± 3.73 11.27 ± 5.11 0.010
UN n-CSA above elbow* 7.72, (IQR 6.7–9.3) 10.93, (IQR 8.4–18.4) 10.73, (IQR 9.4–14.3) 8.76, (IQR 7.5–10.8) 0.014
UN n-CSA mid-arm* 6.92 ± 1.76 10.42 ± 4.24 11.17 ± 4.10 8.00 ± 1.64 0.031
UN f-CSA Guyon 0.68, (IQR 0.5–1.1) 0.72, (IQR 0.4–1.1) 0.86, (IQR 0.7–2) 1.25 (IQR 0.71.8) 0.245
UN f-CSA mid-forearm* 0.71, (IQR 0.5–0.7) 0.99, (IQR 0.8–1.3) 1.33, (IQR 0.9–2.3) 1.09, (IQR 0.7–1.6) 0.004
UN f-CSA below elbow* 0.82, (IQR 0.5–1.5) 1.32, (IQR 1–2.4) 1.86 (IQR 0.9–2.4) 3.87, (IQR 1.7–8.6) 0.019
UN f-CSA elbow 1.98, (IQR 1.5–3.2) 3, (IQR 2–3) 1.66, (IQR 1.4–4.7) 5.56, (IQR 2–11) 0.422
UN f-CSA above elbow* 1.42, (IQR 1–1.8) 1.82, (IQR 1.8–2.3) 3, (IQR 2.1–4) 3.47, (IQR 1.7–6.5) 0.010
UN f-CSA mid-arm* 1.16, (IQR 0.9–1.2) 1.21, (IQR 1–1.4) 2.79, (IQR 1.7–3.4) 3.3, (IQR 1.1–5) 0.010
Average MN CSA* 10.23 ± 1.10 13.74 ± 2.30 14.19 ± 3.85 11.18 ± 2.69 0.002
Average MN f-CSA* 1.17 ± .41 1.65 ± .39 3.19 ± 1.59 2.86 ± .94  < 0.001
Average UN CSA* 7.51, (IQR 6.58.2) 10.81, (IQR 7.9–13.8) 9.29, (IQR 8.32–10.8) 8.24, (IQR 7.3–9.6) 0.005
Average UN f-CSA* 1.25, (IQR 1–1.4) 1.58, (IQR 1.4–2.5) 1.94, (IQR 1.5–2.9) 2.59, (IQR 2–4.6) 0.001
MN FR wrist 0.07 ± 0.02 0.07 ± 0.02 0.08 ± 0.02 0.07 ± 0.04 0.964
MN FR mid-forearm 0.10 ± 0.03 0.10 ± 0.05 0.12 ± 0.05 0.13 ± 0.07 0.509
MN FR antecubital fossa* 0.12 ± 0.06 0.12 ± 0.05 0.29 ± 0.19 0.41 ± 0.31 0.021
MN FR mid-arm* 0.10, (IQR 0.1–0.2) 0.14, (IQR 0.1–0.3) 0.30, (IQR 0.1–0.4) 0.57, (IQR 0.3–0.9) 0.006
UN FR Guyon 0.11, (IQR 0.08–0.2) 0.12, (IQR 0.06–0.2) 0.13, (IQR 0.1–0.2) 0.19, (IQR 0.1–0.2) 0.506
UN FR mid-forearm* 0.12, (IQR 0.07–0.1) 0.13, (IQR 0.1–0.2) 0.16, (IQR 0.1–0.2) 0.18, (IQR 0.1–0.2) 0.041
UN FR below elbow* 0.11, (IQR 0.07–0.2) 0.18, (IQR 0.1–0.3) 0.16, (IQR 0.09–0.2) 0.65, (IQR 0.2–1) 0.049
UN FR elbow 0.21, (IQR 0.2–0.3) 0.20, (IQR 0.1–0.3) 0.18, (IQR 0.1–0.4) 0.40, (IQR 0.2–0.7) 0.186
UN FR above elbow 0.18 ± 0.07 0.17 ± 0.08 0.26 ± 0.12 0.42 ± 0.33 0.171
UN FR mid-arm* 0.18 ± 0.06 0.13 ± 0.06 0.27 ± 0.10 0.40 ± 0.34 0.024
Largest MN n-CSA* 13.08 (1.75) 18.51 (5.59) 18.53 (5.59) 14.42 (4.91) 0.018
Largest MN f-CSA* 1.89 (1.10) 3.10 (0.88) 6.08 (3.21) 5.14 (1.66)  < 0.001
Largest UN n-CSA* 9.80, IQR 8.99–11.19 17.57, IQR 11.19–20.49 11.97, IQR 11.12–13.86 11.04, IQR 9.31–15.11 0.006
Largest UN f-CSA* 2.34, IQR 1.563.36 3.00, IQR 2.35–6.56 3.65, IQR 2.91–4.90 5.81, 3.01–12.25 0.037

Significance values in Bold.

*Asterisks show statistical significance.